Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | NCK1 | P16333 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363012 | 0.82 | TDP1 (0.52) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL21985898 | 0.81 | TDP1 (0.56) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL8168153 | 0.79 | TDP1 (0.45) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL5084622 | 0.78 | TDP1 (0.44) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL18105295 | 0.78 | TDP1 (0.43) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL8342343 | 0.77 | TDP1 (0.52) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL6257642 | 0.77 | TDP1 (0.52) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL3680895 | 0.76 | CASP1 (0.42) | TDP1CYP3A4TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL14926 | 0.76 | AMY1A (0.44) | TDP1CYP3A4TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL29354308 | 0.76 | AMY1A (0.44) | TDP1CYP3A4TP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336749-B | Preparation method of indoloquinoline compound | 湖北工业大学 | 2022-04-29 | — | — | CN | claimed |
| CN-113336749-A | Preparation method of indoloquinoline compound | 湖北工业大学 | 2021-09-03 | — | — | CN | claimed |
| US-8329814-B2 | Ink formulations, modified pigment-based ink formulations and methods of making | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2012-12-11 | — | — | US | claimed |
| CN-117946104-A | Preparation method of iodine-mediated indolo [2,3-b ] quinoline compound in water phase | 山东第二医科大学 | 2024-04-30 | — | — | CN | disclosed |
| EP-2970176-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-112778347-B | Synthetic method of boron nitrogen benzocarbazole derivative | 九江善水科技股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-113336749-B | Preparation method of indoloquinoline compound | 湖北工业大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-113336749-B | Preparation method of indoloquinoline compound | 湖北工业大学 | 2022-04-29 | — | — | CN | disclosed |
| EP-3237385-B1 | MUTANT IDH1 INHIBITORS USEFUL FOR TREATING CANCER | US HEALTH (US) | 2021-11-24 | — | — | EP | disclosed |
| CN-113336749-A | Preparation method of indoloquinoline compound | 湖北工业大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113336749-A | Preparation method of indoloquinoline compound | 湖北工业大学 | 2021-09-03 | — | — | CN | disclosed |
| WO-2016106331-A1 | MUTANT IDH1 INHIBITORS USEFUL FOR TREATING CANCER | THE UNITED STATES OF AMERICA (US) | 2016-06-30 | — | — | WO | disclosed |
| US-8329814-B2 | Ink formulations, modified pigment-based ink formulations and methods of making | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100179278-A1 | Ink Formulations, Modified Pigment-based Ink Formulations And Methods Of Making | MA ZEYING | 2010-07-15 | — | — | US | disclosed |
| US-7728062-B2 | Ink formulations, modified pigment-based ink formulations and methods of making | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20090247687-A1 | INK FORMULATIONS, MODIFIED PIGMENT-BASED INK FORMULATIONS AND METHODS OF MAKING | MA ZEYING | 2009-10-01 | — | — | US | disclosed |
| US-7563842-B2 | Ink formulations, modified pigment-based ink formulations and methods of making | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2009-07-21 | — | — | US | disclosed |
| US-20060106132-A1 | ink jet; high gloss; pigment is attached pendant to a graft polymer of aminoethanethiolated maleic anhydride-styrene and amine terminated PEG or PPG; pigment can be carbon black having attached 2-(mercaptoethylsulfonephenyl) group | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-05-18 | — | — | US | disclosed |
| CN-1114497-C | Preparation method of self-solidified 'after cyclopentadiene' nickel base olefinic polymerization catalyst | CHANGCHUN APPLIED CHEMISTRY (CN) | 2003-07-16 | — | — | CN | disclosed |
| CN-1328879-A | Preparation method of self-solidified 'after cyclopentadiene' nickel base olefinic polymerization catalyst | CHANGCHUN APPLIED CHEMISTRY (CN) | 2002-01-02 | — | — | CN | disclosed |