Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925035 | 1.00 | LMNA (0.59) | LMNATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL24619346 | 1.00 | LMNA (0.59) | LMNATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL29925022 | 1.00 | LMNA (0.59) | LMNATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL24619254 | 1.00 | LMNA (0.59) | LMNATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL24741120 | 0.87 | LMNA (0.67) | LMNATHRBMAPTTP53 | |
| SCHEMBL24741259 | 0.87 | LMNA (0.67) | LMNATHRBMAPTTP53 | |
| SCHEMBL29925365 | 0.85 | MAPT (0.51) | LMNATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL29925232 | 0.81 | LMNA (0.50) | LMNATHRBMAPTALDH1A1KDM4E | |
| SCHEMBL24619267 | 0.81 | LMNA (0.72) | LMNATHRBMAPTTP53 | |
| SCHEMBL29925288 | 0.81 | LMNA (0.72) | LMNATHRBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |