Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925371 | 0.89 | LMNA (0.56) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL30086063 | 0.86 | LMNA (0.48) | LMNATP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL24619976 | 0.85 | LMNA (0.55) | LMNATP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL29925365 | 0.84 | MAPT (0.51) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL24619796 | 0.83 | LMNA (0.62) | LMNATP53MAPTTHRBRXFP1 | |
| SCHEMBL29925271 | 0.83 | MAPT (0.49) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL29925227 | 0.82 | MAPT (0.50) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL30086015 | 0.82 | LMNA (0.54) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL24619346 | 0.81 | LMNA (0.59) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL24619254 | 0.81 | LMNA (0.59) | LMNATP53MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |