SCHEMBL29924872

SCHEMBL29924872

CCN(CCCNC(=O)c1ccc2c(c1)sc1nc(-c3ccc(C(=O)NC)cc3)cn12)C(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.65
▸ TP53 P04637 5/20 0.58
▸ LMNA P02545 3/20 0.57
▸ THRB P10828 3/20 0.54
▸ POLB P06746 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619416 1.00 MAPT (0.65) MAPTTP53LMNATHRBPOLB
SCHEMBL29925044 0.89 MAPT (0.65) MAPTTP53LMNATHRBPOLB
SCHEMBL29925154 0.89 MAPT (0.59) MAPTTP53LMNATHRBPOLB
SCHEMBL24619398 0.86 MAPT (0.85) MAPTTP53LMNATHRBPOLB
SCHEMBL29924744 0.86 MAPT (0.85) MAPTTP53LMNATHRBPOLB
SCHEMBL24619961 0.82 TP53 (0.66) MAPTTP53LMNATHRBPOLB
SCHEMBL24619803 0.82 LMNA (0.68) MAPTTP53LMNATHRBPOLB
SCHEMBL29925356 0.81 MAPT (0.58) MAPTTP53LMNATHRBPOLB
SCHEMBL24741269 0.81 LMNA (0.68) MAPTTP53LMNATHRBPOLB
SCHEMBL30086022 0.81 MAPT (0.73) MAPTTP53LMNATHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 — — WO disclosed
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