Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924872 | 0.89 | MAPT (0.65) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL24619416 | 0.89 | MAPT (0.65) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL24619803 | 0.84 | LMNA (0.68) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL24619961 | 0.83 | TP53 (0.66) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL29924744 | 0.82 | MAPT (0.85) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL24619398 | 0.82 | MAPT (0.85) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL29925048 | 0.81 | TP53 (0.68) | MAPTLMNATP53THRBPOLB | |
| Formic Acid SCHEMBL29925647 | 0.81 | LMNA (0.64) | MAPTLMNATP53THRBPOLB | |
| SCHEMBL24619719 | 0.81 | LMNA (0.68) | MAPTLMNATP53THRB | |
| SCHEMBL29925034 | 0.81 | LMNA (0.57) | MAPTLMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |