Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218767 | 0.83 | SLC7A5 (0.50) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL17351893 | 0.83 | TSHR (0.46) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL15937178 | 0.83 | TSHR (0.46) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL29728550 | 0.81 | LMNA (0.48) | LMNATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL28623541 | 0.79 | — | — | |
| SCHEMBL28623543 | 0.79 | — | — | |
| SCHEMBL14627140 | 0.78 | — | — | |
| SCHEMBL745345 | 0.78 | — | — | |
| SCHEMBL14627973 | 0.77 | — | — | |
| Pentabamate SCHEMBL636717 | 0.76 | LMNA (0.44) | LMNATSHRCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022191918-A1 | SYSTEMS AND METHODS FOR DETECTING NEW DRUG PROPERTIES IN TARGET-BASED DRUG-DRUG SIMILARITY NETWORKS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2022-09-15 | — | — | WO | disclosed |