Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349853 | 0.98 | CES2 (0.54) | CES2CES1BCHEPARP1ALB | |
| SCHEMBL11266406 | 0.98 | CES2 (0.54) | CES2CES1BCHEPARP1ALB | |
| SCHEMBL10950165 | 0.86 | ALB (0.52) | CES2CES1BCHEPARP1ALB | |
| SCHEMBL7121048 | 0.86 | ALB (0.57) | CES2CES1BCHEPARP1ALB | |
| SCHEMBL203321 | 0.84 | CES2 (0.64) | CES2CES1BCHEPARP1ALB | |
| Ammonia Solution, Strong SCHEMBL10951318 | 0.84 | ALB (0.50) | CES2CES1BCHEPARP1ALB | |
| Ammonia Solution, Strong SCHEMBL11279325 | 0.84 | ALB (0.55) | CES2CES1BCHEPARP1ALB | |
| Ammonia Solution, Strong SCHEMBL10950194 | 0.84 | ALB (0.55) | CES2CES1BCHEPARP1ALB | |
| SCHEMBL5723592 | 0.82 | CES2 (0.47) | CES2CES1BCHEALDH1A1MAPT | |
| SCHEMBL11279904 | 0.82 | CES2 (0.47) | CES2CES1BCHEPARP1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115184510-A | Method for detecting residual quantity of novel insecticide bromofenoxanil in fruits and vegetables | 湖南省产商品质量检验研究院 | 2022-10-14 | — | — | CN | disclosed |