SCHEMBL7121048

SCHEMBL7121048

NC(=O)c1c(F)cccc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.57
CES2 O00748 4/20 0.50
CES1 P23141 4/20 0.50
BCHE P06276 1/20 0.45
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 2/20 0.44
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
PARP1 P09874 1/20 0.42
MMP2 P08253 1/20 0.42
ITGB2 P05107 1/20 0.41
ICAM1 P05362 1/20 0.41
ITGAL P20701 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
HMGB1 P09429 1/20 0.41
KMT2A Q03164 1/20 0.40
TTR P02766 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11279325 0.98 ALB (0.55) ALBCES2CES1BCHEALDH1A1
Ammonia Solution, Strong SCHEMBL10950194 0.98 ALB (0.55) ALBCES2CES1BCHEALDH1A1
SCHEMBL29349853 0.88 CES2 (0.54) ALBCES2CES1BCHEALDH1A1
SCHEMBL11266406 0.88 CES2 (0.54) ALBCES2CES1BCHEALDH1A1
Bromide SCHEMBL29924937 0.86 CES2 (0.52) ALBCES2CES1BCHEALDH1A1
SCHEMBL29592539 0.85 ALB (0.63) ALBCES2CES1BCHEALDH1A1
SCHEMBL335939 0.85 ALB (0.63) ALBCES2CES1BCHEALDH1A1
SCHEMBL2411340 0.85 ALDH1A1 (0.55) ALBALDH1A1ALOX15G6PDCASP7
SCHEMBL10950165 0.84 ALB (0.52) ALBCES2CES1BCHEALDH1A1
SCHEMBL203321 0.83 CES2 (0.64) ALBCES2CES1BCHEPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0055630-B1 METHOD FOR THE PREPARATION OF FLUOROPHTHALAMIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 1985-12-18 EP claimed
US-4521616-A Method for the preparation of fluoroanthranilic acids OCCIDENTAL CHEMICAL CORPORATION (US) 1985-06-04 US claimed
US-4374266-A USED AS CHEMICAL INTERMEDIATES IN MAKING FLUORINATED AROMATIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 1983-02-15 US claimed
US-4374267-A USED AS CHEMICAL INTERMEDIATES IN MAKING FLUORINATED AROMATIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 1983-02-15 US claimed
US-4343951-A Method for the preparation of fluoroaniline HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-08-10 US claimed
EP-0055629-A1 Process for preparing fluoroanthranilic compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-07-07 EP claimed
EP-0055630-A2 Method for the preparation of fluorophthalamic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1982-07-07 EP claimed
EP-1094053-B1 Method of preparing fluoroaromatic compounds ZELINSKY INST OF ORGANIC CHEMI (RU) 2003-05-21 EP disclosed
EP-1094053-A1 Method of preparing fluoroaromatic compounds Zelinsky Institute of Organic Chemistry (RU) 2001-04-25 EP disclosed
US-6008407-A REACTING CHLOROTRIFLUOROETHYLENE AND 1,3-BUTADIENE TO PRODUCE CHLOROTRIFLUOROCYCLOHEXENES, DEHYDROHALOGENATING THE MIXTURE OF CYCLOHEXENES WITH PHASE TRANSFER CATALYST IN PRESENCE OF ALKALI METAL HYDROXIDE WITHOUT SOLVENT ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY (RU) 1999-12-28 US disclosed
EP-0055630-B1 METHOD FOR THE PREPARATION OF FLUOROPHTHALAMIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 1985-12-18 EP disclosed
EP-0148366-A2 4,5-difluorophthaloyl fluoride and its preparation OCCIDENTAL CHEMICAL CORPORATION (US) 1985-07-17 EP disclosed
US-4521616-A Method for the preparation of fluoroanthranilic acids OCCIDENTAL CHEMICAL CORPORATION (US) 1985-06-04 US disclosed
US-4343951-A Method for the preparation of fluoroaniline HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-08-10 US disclosed
US-4343951-A Method for the preparation of fluoroaniline HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-08-10 US disclosed
EP-0055629-A1 Process for preparing fluoroanthranilic compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-07-07 EP disclosed
EP-0055629-A1 Process for preparing fluoroanthranilic compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-07-07 EP disclosed
EP-0055630-A2 Method for the preparation of fluorophthalamic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1982-07-07 EP disclosed
EP-0055630-A2 Method for the preparation of fluorophthalamic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1982-07-07 EP disclosed
EP-0055630-A2 Method for the preparation of fluorophthalamic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1982-07-07 EP disclosed