Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | POR | P16435 | 1/20 | 0.46 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078210 | 0.89 | MAPK14 (0.53) | MAPK14AKR1A1AKR1B1CA1CA2 | |
| SCHEMBL28155812 | 0.88 | CA1 (0.57) | CA1CA2CA4CA7CA9 | |
| SCHEMBL2993382 | 0.84 | CA1 (0.53) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7786812 | 0.84 | CA1 (0.57) | CA1CA2CA4CA7CA9 | |
| SCHEMBL13487415 | 0.82 | CA1 (0.52) | AKR1A1AKR1B1CA1CA2CA7 | |
| SCHEMBL2997273 | 0.81 | PTPN1 (0.54) | CA1CA2CA4CA7CA9 | |
| SCHEMBL10885799 | 0.80 | CA1 (0.53) | CA1CA2CA4CA7CA9 | |
| SCHEMBL23111388 | 0.80 | CA1 (0.57) | CA1CA2CA4CA7CA9 | |
| SCHEMBL29595732 | 0.80 | CA1 (0.57) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7451901 | 0.80 | CA1 (0.57) | CA1CA2CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100180937-A1 | HOLOGRAPHIC ENERGY-COLLECTING MEDIUM AND ASSOCIATED DEVICE | GENERAL ELECTRIC COMPANY (US) | 2010-07-22 | — | — | US | disclosed |