SCHEMBL2992529

SCHEMBL2992529

COC(=O)C1=C(C(=O)OC)C(C(=O)OC)=C(C(=O)OC)[Pd]1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 3/20 0.36
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CA12 O43570 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA14 Q9ULX7 3/20 0.34
MAPT P10636 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
KMT2A Q03164 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
NFKB1 P19838 1/20 0.33
XDH P47989 1/20 0.33
GFER P55789 1/20 0.33
NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9063074 0.69 NPSR1 (0.46) NPSR1TSHRCA1CA2CA12
SCHEMBL9242569 0.69 NPSR1 (0.46) NPSR1TSHRCA1CA2CA12
SCHEMBL10260335 0.64 CA1 (0.57) NPSR1TSHRCA1CA2CA12
SCHEMBL9655522 0.62 FGFR1 (0.39) NPSR1TSHRCA1CA2CA12
SCHEMBL21234787 0.62 FGFR1 (0.39) NPSR1TSHRCA1CA2CA12
SCHEMBL7126586 0.62 NPSR1 (0.39) NPSR1TSHRCA1CA2CA12
SCHEMBL14000244 0.62 TSHR (0.39) NPSR1TSHRCA1CA2CA12
SCHEMBL4795656 0.60 CCR6 (0.46) NPSR1TSHRKMT2AHSD17B10KDM4E
SCHEMBL23788873 0.59 CA12 (0.46) NPSR1TSHRCA1CA2CA12
SCHEMBL71518 0.58 NPSR1 (0.59) NPSR1TSHRCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013041106-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS 11CO FOR CARBONYLATION REACTIONS IN THE PREPARATION OF RADIOPHARMACEUTICALS FOR PET IMAGING AARHUS UNIVERSITET (DK) 2013-03-28 WO disclosed
US-8293938-B2 Alkylphosphonous acids, salts and esters, methods for the production thereof, and use of the same CLARIANT FINANCE (BVI) LIMITED (VG) 2012-10-23 US disclosed
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed
US-20100190901-A1 Alkylphosphonous Acids, Salts and Esters, Methods for the Production Thereof, and Use of the Same CLARIANT FINANCE (BVI) LIMITED (VG) 2010-07-29 US disclosed