Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600521 | 0.83 | FDPS (0.40) | FDPSDNM1SMPD1 | |
| SCHEMBL16936158 | 0.82 | SMPD1 (0.45) | FDPSDNM1SMPD1 | |
| SCHEMBL3210177 | 0.82 | SMPD1 (0.45) | FDPSDNM1SMPD1 | |
| SCHEMBL3207013 | 0.82 | SMPD1 (0.45) | FDPSDNM1SMPD1 | |
| SCHEMBL16936118 | 0.82 | SMPD1 (0.45) | FDPSDNM1SMPD1 | |
| SCHEMBL272022 | 0.81 | DNM1 (0.46) | FDPSDNM1SMPD1 | |
| Fluoride SCHEMBL28863769 | 0.80 | FDPS (0.37) | FDPSSMPD1 | |
| SCHEMBL6742987 | 0.80 | FDPS (0.41) | FDPSDNM1SMPD1 | |
| Fluoride SCHEMBL2965507 | 0.80 | FDPS (0.37) | FDPSSMPD1 | |
| SCHEMBL6790923 | 0.78 | FDPS (0.42) | FDPSDNM1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100187467-A1 | Aqueous solution for formation of clathrate hydrate, heat storage agent, method for producing clathrate hydrate or its slurry, heat accumulating and radiating method and method for preparing aqueous solution to produce latent heat storage agent or its major component | JFE ENGINEERING CORPORATION | 2010-07-29 | — | — | US | disclosed |
| EP-2210928-A1 | AQUEOUS SOLUTION FOR CLATHRATE HYDRATE FORMATION, HEAT-STORAGE AGENT, PROCESS FOR PRODUCING CLATHRATE HYDRATE OR SLURRY THEREOF, METHOD OF STORING/RADIATING HEAT, AND PROCESS FOR PREPARING AQUEOUS SOLUTION FOR FORMING LATENT-HEAT-STORAGE AGENT OR MAJOR COMPONENT THEREOF | JFE Engineering Corporation (JP) | 2010-07-28 | — | — | EP | disclosed |