Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925414 | 0.88 | FPR2 (0.34) | KDM1AFPR2KCNH2LMNAPGR | |
| SCHEMBL29924718 | 0.88 | FPR2 (0.34) | KDM1AFPR2KCNH2LMNAPGR | |
| SCHEMBL30085699 | 0.85 | HRH3 (0.39) | KDM1AFPR2KCNH2HRH3LMNA | |
| SCHEMBL29924842 | 0.84 | CACNA1C (0.32) | AKT1MKNK1 | |
| SCHEMBL29925052 | 0.84 | CACNA1C (0.32) | AKT1MKNK1 | |
| SCHEMBL30085708 | 0.83 | HRH3 (0.37) | KDM1AFPR2KCNH2HRH3ADRA1D | |
| SCHEMBL30085724 | 0.81 | HRH3 (0.36) | KDM1AFPR2HRH3 | |
| SCHEMBL30085768 | 0.76 | KDM4E (0.38) | KDM1AFPR2KCNH2HRH3ACHE | |
| SCHEMBL29924781 | 0.75 | FPR2 (0.34) | KDM1AFPR2KCNH2HRH3ACHE | |
| SCHEMBL29924699 | 0.75 | FPR2 (0.34) | KDM1AFPR2KCNH2ADRA1DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |