Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 7/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925414 | 1.00 | FPR2 (0.34) | FPR2PARP1PARP2MAP4K4CSF1R | |
| SCHEMBL29925527 | 0.88 | KDM1A (0.33) | FPR2KDM1ALMNAPGRCHRM2 | |
| SCHEMBL29924650 | 0.82 | FPR2 (0.36) | FPR2KDM1ASLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL29925004 | 0.77 | KCNH2 (0.44) | HTR1AADRA2ADRD1SLC6A2SLC6A4 | |
| SCHEMBL30085699 | 0.76 | HRH3 (0.39) | FPR2KDM1ALMNAKCNH2 | |
| SCHEMBL29924990 | 0.75 | ADRA1D (0.33) | FPR2KDM1A | |
| SCHEMBL29925063 | 0.74 | CD274 (0.37) | FPR2KDM1ALMNACHRM2HTR1A | |
| SCHEMBL29924842 | 0.73 | CACNA1C (0.32) | — | |
| SCHEMBL30085724 | 0.73 | HRH3 (0.36) | FPR2KDM1AL3MBTL1 | |
| SCHEMBL30085708 | 0.73 | HRH3 (0.37) | FPR2KDM1ALMNACHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |