Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 6/20 | 0.60 |
| ▸ | WNT3A | P56704 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145658 | 1.00 | CTNNB1 (0.60) | CTNNB1WNT3AMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9959381 | 0.99 | CTNNB1 (0.59) | CTNNB1WNT3AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL562951 | 0.88 | MEN1 (0.65) | CTNNB1WNT3AMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL731312 | 0.87 | MEN1 (0.64) | CTNNB1WNT3AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16596006 | 0.86 | DHODH (0.59) | CTNNB1WNT3AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24076596 | 0.86 | ROCK2 (0.56) | JAK2JAK3MMP2MMP13 | |
| SCHEMBL6017068 | 0.85 | CTNNB1 (0.53) | CTNNB1WNT3AMEN1KMT2ARAB9A | |
| SCHEMBL4414068 | 0.84 | CTNNB1 (0.53) | CTNNB1WNT3AMEN1KMT2ACYP2D6 | |
| Urethane SCHEMBL5780178 | 0.83 | CTNNB1 (0.55) | CTNNB1WNT3AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29643714 | 0.83 | NPC1 (0.58) | CTNNB1WNT3AMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308570-A1 | MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022194976-A1 | MACROCYCLIC LRRK2 KINASE INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2022-09-22 | — | — | WO | disclosed |