Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.53 |
| ▸ | WNT3A | P56704 | 7/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.44 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017068 | 0.86 | CTNNB1 (0.53) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL145658 | 0.84 | CTNNB1 (0.60) | CTNNB1WNT3ANPC1RAB9AMEN1 | |
| SCHEMBL29925697 | 0.84 | CTNNB1 (0.60) | CTNNB1WNT3ANPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL9959381 | 0.83 | CTNNB1 (0.59) | CTNNB1WNT3ANPC1RAB9AMEN1 | |
| SCHEMBL29643714 | 0.79 | NPC1 (0.58) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL348190 | 0.79 | NPC1 (0.58) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL465188 | 0.78 | HRH3 (0.50) | SLC6A2 | |
| SCHEMBL22529634 | 0.76 | ROCK2 (0.53) | CTNNB1WNT3AMAOBROCK2ROCK1 | |
| SCHEMBL30074092 | 0.75 | CTNNB1 (0.53) | CTNNB1WNT3AMAOBNPC1RAB9A | |
| SCHEMBL27836080 | 0.75 | CTNNB1 (0.53) | CTNNB1WNT3AMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | disclosed |
| EP-1628972-A1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004101556-A1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |