Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 7/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926348 | 0.85 | ERBB2 (0.45) | ACVRL1ERBB2EGFRBTK | |
| SCHEMBL29927002 | 0.85 | ACVRL1 (0.46) | ACVRL1ERBB2BTK | |
| SCHEMBL29926737 | 0.84 | ERBB2 (0.60) | ERBB2EGFR | |
| SCHEMBL29926730 | 0.83 | ERBB2 (0.47) | ERBB2EGFR | |
| SCHEMBL29926948 | 0.76 | ERBB2 (0.54) | ERBB2EGFR | |
| SCHEMBL28630028 | 0.76 | ERBB2 (0.54) | ERBB2EGFR | |
| SCHEMBL28630033 | 0.76 | ERBB2 (0.54) | ERBB2EGFR | |
| SCHEMBL30244942 | 0.73 | ERBB2 (0.71) | ERBB2EGFR | |
| SCHEMBL29926876 | 0.71 | ERBB2 (0.64) | ERBB2EGFR | |
| SCHEMBL29927100 | 0.69 | ERBB2 (0.59) | ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336760-B | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-11-04 | — | — | CN | disclosed |