Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187080 | 0.86 | KMT2A (0.51) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL29927042 | 0.81 | TSHR (0.61) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4256368 | 0.80 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL29927442 | 0.79 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL29927010 | 0.78 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL29926864 | 0.78 | KCNK3 (0.61) | NPC1RAB9AKMT2AALDH1A1KCNK9 | |
| SCHEMBL10055020 | 0.78 | NPC1 (0.94) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL29927158 | 0.77 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29927583 | 0.77 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL20239535 | 0.76 | MAOB (0.54) | NPC1RAB9ASMN1; SMN2KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299371-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | UNIV TEXAS (US) | 2024-09-12 | — | — | US | claimed |
| WO-2022197740-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-09-22 | — | — | WO | claimed |
| US-20240299371-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | UNIV TEXAS (US) | 2024-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299371-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | AADAC, BET1, ERG28 | NPC1 2429/4885RAB9A 2286/4885SMN1; SMN2 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.