Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187080 | 0.82 | KMT2A (0.51) | TSHRSMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL6174341 | 0.81 | TSHR (0.75) | TSHRSMN1; SMN2KDRKMT2ACYP1A2 | |
| SCHEMBL29927101 | 0.81 | NPC1 (0.65) | SMN1; SMN2KMT2ACYP1A2CYP2C9KCNK3 | |
| SCHEMBL29927158 | 0.80 | NPC1 (0.53) | TSHRSMN1; SMN2KMT2AKCNK3MAPK1 | |
| SCHEMBL29927602 | 0.79 | TSHR (0.62) | TSHRSMN1; SMN2KDRKMT2ACYP1A2 | |
| SCHEMBL29927529 | 0.78 | TSHR (0.61) | TSHRSMN1; SMN2KDRKMT2ACYP1A2 | |
| SCHEMBL4653584 | 0.77 | SMN1; SMN2 (1.00) | TSHRSMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL29926864 | 0.74 | KCNK3 (0.61) | KMT2AKCNK3MEN1NPC1ALDH1A1 | |
| SCHEMBL20239535 | 0.74 | MAOB (0.54) | SMN1; SMN2KMT2ANR1H4MEN1NPC1 | |
| SCHEMBL6174665 | 0.74 | KMT2A (0.73) | TSHRSMN1; SMN2KDRKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299371-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | UNIV TEXAS (US) | 2024-09-12 | — | — | US | claimed |
| US-20240299371-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | UNIV TEXAS (US) | 2024-09-12 | — | — | US | disclosed |
| WO-2022197740-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299371-A1 | BIARYL AMIDE AND HETEROARYL AMIDES FOR TREATMENT OF CANDIDA ALBICANS INFECTION | AADAC, BET1, ERG28 | TSHR 4194/4885SMN1; SMN2 4882/4885KDR 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.