Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328242 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29571817 | 0.91 | TDP1 (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL45823 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31084748 | 0.87 | NOTUM (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2944059 | 0.87 | NOTUM (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10400378 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| 4-Methylbenzoic Acid Methyl Ester SCHEMBL29962867 | 0.86 | TDP1 (0.67) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL30967314 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL1018113 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9080431 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| EP-4430052-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | Nurix Therapeutics, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118580241-A | Tetrahydropyrrolo [3,4-c ] pyrazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118451078-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2024121779-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| CN-112955448-B | Aromatic ring or aromatic heterocyclic compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113621175-B | Efficient isotactic polypropylene beta-crystal form nucleating agent and preparation method and application thereof | 中国科学院化学研究所 | 2022-10-18 | — | — | CN | disclosed |