SCHEMBL1018113

SCHEMBL1018113

COC(=O)c1ccc(C(=O)O)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.53
HSD17B10 Q99714 4/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 2/20 0.53
ATM Q13315 2/20 0.53
GLA P06280 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
KDM6B O15054 1/20 0.49
KDM5C P41229 1/20 0.49
KDM4C Q9H3R0 1/20 0.49
KDM2A Q9Y2K7 1/20 0.49
KDM3A Q9Y4C1 1/20 0.49
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45823 0.88 KDM4E (0.67) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL29571817 0.87 TDP1 (0.53) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL1170268 0.87 KDM4E (0.47) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL2888346 0.86 KDM4E (0.55) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL820141 0.86 KDM4E (0.55) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL29699657 0.86 KDM4E (0.55) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL11328242 0.85 KDM4E (0.58) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL29927249 0.85 KDM4E (0.58) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL293610 0.85 KDM4E (0.53) KDM4EHSD17B10ALDH1A1HPGDATM
SCHEMBL30928356 0.85 KDM4E (0.53) KDM4EHSD17B10ALDH1A1HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3595808-B1 ORGANIC - INORGANIC POROUS HYBRID MATERIAL, METHOD FOR OBTAINING IT AND USE THEREOF INDUSTRIAS QUIM DEL EBRO S A (ES) 2020-08-05 EP claimed
CN-107383079-B Metal organic framework material based on alkyl mercaptan modification and synthetic method thereof 广东工业大学 2020-06-09 CN claimed
CN-107337626-B A kind of alkyl hydrosulfide functionalization aromatic carboxylic acids and preparation method thereof 广东工业大学 2019-04-12 CN claimed
WO-2018167078-A1 ORGANIC - INORGANIC POROUS HYBRID MATERIAL, METHOD FOR OBTAINING IT AND USE THEREOF UNIVERSIDAD DE ZARAGOZA (ES) 2018-09-20 WO claimed
US-8921083-B2 Modified microorganism for high efficient production of 1,4-butanediol SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-12-30 US claimed
US-20140030773-A1 MODIFIED MICROORGANISM FOR HIGH EFFICIENT PRODUCTION OF 1,4-BUTANEDIOL SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-01-30 US claimed
EP-2690109-A1 Modified microorganism for high efficient production of 1,4-butanediol Samsung Electronics Co., Ltd (KR) 2014-01-29 EP claimed
WO-2007027027-A1 BIODEGRADABLE POLYESTER COMPOSITION HAVING BARRIER PROPERTY LG CHEM, LTD. (KR) 2007-03-08 WO claimed
EP-1036105-A1 PREPARATION OF POLYESTERS AND ESTERS FROM COMPOUNDS CONTAINING SECONDARY HYDROXYL GROUPS EASTMAN CHEMICAL COMPANY (US) 2000-09-20 EP claimed
WO-1999028368-A1 PREPARATION OF POLYESTERS AND ESTERS FROM COMPOUNDS CONTAINING SECONDARY HYDROXYL GROUPS EASTMAN CHEMICAL COMPANY (US) 1999-06-10 WO claimed
EP-0724559-B1 PROCESS FOR SEPARATING CYCLOHEXANE DIMETHANOL FROM DIMETHYL TEREPHTHALATE EASTMAN CHEM CO (US) 1998-12-30 EP claimed
EP-0724559-A1 PROCESS FOR SEPARATING CYCLOHEXANE DIMETHANOL FROM DIMETHYL TEREPHTHALATE EASTMAN CHEMICAL COMPANY (US) 1996-08-07 EP claimed
US-5480411-A KNOT SECURITY, CREEP RESISTANCE; SURGERY UNITED STATES SURGICAL CORPORATION (US) 1996-01-02 US claimed
WO-1995011218-A1 PROCESS FOR SEPARATING CYCLOHEXANE DIMETHANOL FROM DIMETHYL TEREPHTHALATE EASTMAN CHEMICAL COMPANY (US) 1995-04-27 WO claimed
EP-0318788-A2 Improved nucleated thermoplastic copolyetherester molding compositions GENERAL ELECTRIC COMPANY (US) 1989-06-07 EP claimed
EP-0144281-B1 HIGH SOLIDS THEIC POLYESTER ENAMELS ESSEX GROUP INC. (US) 1988-01-20 EP claimed
US-4707274-A Multistage arrangement for countercurrent separation and methods of operating same AMBERGER KAOLINWERKE GMBH (DE) 1987-11-17 US claimed
US-20260145405-A1 POLYMERIC NONWOVEN STRUCTURE FOR USE IN HIGH TEMPERATURE APPLICATIONS ZEPHYROS, INC. (US) 2026-05-28 US disclosed
US-3984607-A VINYL COPOLYMER AND A DIENE GRAFT COPOLYMER BAYER AKTIENGESELLSCHAFT (DT) 1976-10-05 US disclosed
US-3972877-A Butadiene derivatives, process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260145405-A1 POLYMERIC NONWOVEN STRUCTURE FOR USE IN HIGH TEMPERATURE APPLICATIONS MYOF, MB, MYH10 KDM4E 1423/4885HSD17B10 3940/4885ALDH1A1 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.