Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.51 |
| ▸ | INSR | P06213 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 8/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | USP10 | Q14694 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | USP13 | Q92995 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928392 | 0.83 | AXL (0.53) | AXLINSRHTTKDRATM | |
| SCHEMBL30090637 | 0.75 | AXL (0.55) | AXLINSRHTTKDRATM | |
| SCHEMBL29927676 | 0.74 | ATM (0.69) | AXLINSRKDRATMPIK3CA | |
| SCHEMBL18312194 | 0.70 | MAP4K4 (0.74) | MAP4K4 | |
| SCHEMBL29728028 | 0.70 | MAP4K4 (0.74) | MAP4K4 | |
| SCHEMBL29928613 | 0.69 | HTR2C (0.47) | AXLINSRKDRATMPIK3CA | |
| SCHEMBL29928021 | 0.69 | KDR (0.50) | AXLHTTKDRMAP4K4PIK3CA | |
| SCHEMBL21456824 | 0.69 | HTT (0.58) | AXLINSRHTTMAP4K4CHRM4 | |
| SCHEMBL858063 | 0.67 | PDE4A (0.53) | HTTMAP4K4USP10PIK3C3USP13 | |
| SCHEMBL29461081 | 0.67 | PDE4A (0.53) | HTTMAP4K4USP10PIK3C3USP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |