Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21252166 | 0.81 | TSHR (0.42) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL20331989 | 0.81 | TSHR (0.42) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL31513601 | 0.79 | CYP1A2 (0.45) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL24358382 | 0.78 | L3MBTL1 (0.42) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL25648931 | 0.78 | L3MBTL1 (0.40) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL22234497 | 0.78 | L3MBTL1 (0.40) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL9625796 | 0.77 | L3MBTL1 (0.54) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL2665681 | 0.77 | L3MBTL1 (0.54) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL21386681 | 0.77 | L3MBTL1 (0.48) | TSHRALDH1A1CYP1A2CHRM2OPRM1 | |
| SCHEMBL21878322 | 0.77 | ALDH1A1 (0.41) | TSHRALDH1A1CYP1A2CHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115190813-B | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-115190813-A | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2022-10-14 | — | — | CN | disclosed |