Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492750 | 0.84 | CA1 (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5863502 | 0.83 | CYP1A2 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL23361401 | 0.81 | CA1 (0.46) | CA1CA2CA12CA7CA9 | |
| Lithium SCHEMBL31223142 | 0.80 | CYP2C19 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL26015017 | 0.80 | CA1 (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7677910 | 0.80 | CA12 (0.52) | CA1CA2CA12CA7CA9 | |
| Lithium Ion SCHEMBL26134628 | 0.79 | CA1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16622900 | 0.77 | KDM4E (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1664013 | 0.74 | CA12 (0.75) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13610397 | 0.73 | KMT2A (0.46) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184771-A1 | Bicyclic Heterocyclic Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-1961754-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184771-A1 | Bicyclic Heterocyclic Compound | NR3C2, NR3C1, CRHR1 | CA1 603/4885CA2 917/4885CA12 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.