Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123529 | 0.94 | NAALAD2 (0.60) | MMENAALAD2POLBLTA4HSLC15A1 | |
| SCHEMBL22649263 | 0.94 | NAALAD2 (0.60) | MMENAALAD2POLBLTA4HSLC15A1 | |
| SCHEMBL30671936 | 0.91 | NAALAD2 (0.55) | MMENAALAD2POLBLTA4HSLC15A1 | |
| SCHEMBL30788339 | 0.90 | MME (0.64) | MME | |
| SCHEMBL30567413 | 0.90 | MME (0.67) | MME | |
| SCHEMBL6237394 | 0.88 | NAALAD2 (0.64) | NAALAD2POLBLTA4HSLC15A1GNPAT | |
| SCHEMBL27652943 | 0.88 | NAALAD2 (0.64) | NAALAD2POLBLTA4HSLC15A1GNPAT | |
| SCHEMBL6236774 | 0.88 | NAALAD2 (0.68) | MMENAALAD2POLBLTA4HSLC15A1 | |
| SCHEMBL3048911 | 0.88 | NAALAD2 (0.68) | MMENAALAD2POLBLTA4HSLC15A1 | |
| SCHEMBL3048908 | 0.88 | NAALAD2 (0.68) | MMENAALAD2POLBLTA4HSLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624074-B2 | Polypeptides related to HMGB1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2026-05-12 | — | — | US | disclosed |
| EP-4341280-A1 | POLYPEPTIDES RELATED TO HMGB1 USEFUL FOR PROMOTING TISSUE REGENERATION, COMPOSITIONS COMPRISING SAME, AND USES THEREOF | Oxford University Innovation Limited (GB) | 2024-03-27 | — | — | EP | disclosed |
| US-20230046828-A1 | Polypeptides Related to HMGB1 Useful for Promoting Tissue Regeneration, Compositions Comprising Same, and Uses Thereof | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-02-16 | — | — | US | disclosed |
| WO-2022243932-A1 | POLYPEPTIDES RELATED TO HMGB1 USEFUL FOR PROMOTING TISSUE REGENERATION, COMPOSITIONS COMPRISING SAME, AND USES THEREOF | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-11-24 | — | — | WO | disclosed |
| EP-4058033-A1 | POLYPEPTIDES RELATED TO HMGB1 USEFUL FOR PROMOTING TISSUE REGENERATION, COMPOSITIONS COMPRISING SAME, AND USES THEREOF | Oxford University Innovation Limited (GB) | 2022-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624074-B2 | Polypeptides related to HMGB1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof | HMGB1, HMGB2, HMGB3 | MME 2728/4885NAALAD2 1695/4885POLB 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.