Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | GEMIN4 | P57678 | 1/20 | 0.64 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | F13A1 | P00488 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curvularin SCHEMBL15256930 | 1.00 | MAPT (0.64) | MAPTGEMIN4HSF1NPC1MITF | |
| Curvularin SCHEMBL2140562 | 1.00 | MAPT (0.64) | MAPTGEMIN4HSF1NPC1MITF | |
| Curvularin SCHEMBL30556710 | 1.00 | MAPT (0.64) | MAPTGEMIN4HSF1NPC1MITF | |
| Xestodecalactone A SCHEMBL2874661 | 0.95 | MAPT (0.67) | MAPTGEMIN4HSF1NPC1MITF | |
| SCHEMBL18543028 | 0.83 | MAPT (0.61) | MAPTGEMIN4HSF1NPC1MITF | |
| SCHEMBL15258429 | 0.80 | LMNA (0.80) | MAPTGEMIN4HSF1NPC1MITF | |
| SCHEMBL869065 | 0.79 | LMNA (0.88) | MAPTLMNASMN1; SMN2ESR2ALDH1A1 | |
| SCHEMBL29737259 | 0.79 | LMNA (0.88) | MAPTLMNASMN1; SMN2ESR2ALDH1A1 | |
| SCHEMBL31217635 | 0.79 | LMNA (0.88) | MAPTLMNASMN1; SMN2ESR2ALDH1A1 | |
| SCHEMBL30163150 | 0.79 | LMNA (0.88) | MAPTLMNASMN1; SMN2ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |