Fustin

Fustin

SCHEMBL29929489

O=C1c2ccc(O)cc2OC(c2ccc(O)c(O)c2)C1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.77
NSD2 O96028 1/20 0.77
TDO2 P48775 1/20 0.77
KDM4E B2RXH2 3/20 0.67
CYP3A4 P08684 3/20 0.67
HSD17B10 Q99714 3/20 0.67
RECQL P46063 2/20 0.67
MAPT P10636 2/20 0.67
ALOX15 P16050 2/20 0.67
MAPK1 P28482 2/20 0.67
SOST Q9BQB4 2/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
GAA P10253 2/20 0.67
NFKB1 P19838 2/20 0.67
POLB P06746 1/20 0.67
CYP1A2 P05177 1/20 0.67
ALOX12 P18054 1/20 0.67
HIF1A Q16665 1/20 0.67
ESR1 P03372 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fustin SCHEMBL13640269 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Fustin SCHEMBL555237 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Fustin SCHEMBL13583362 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Fustin SCHEMBL30443589 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
SCHEMBL12378836 0.89 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
SCHEMBL12417567 0.89 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Garbanzol SCHEMBL29370332 0.88 ESR1 (0.73) IDO1NSD2TDO2KDM4ECYP3A4
Garbanzol SCHEMBL9663852 0.88 ESR1 (0.73) IDO1NSD2TDO2KDM4ECYP3A4
Garbanzol SCHEMBL29929200 0.88 ESR1 (0.73) IDO1NSD2TDO2KDM4ECYP3A4
Dihydrobinetin SCHEMBL18177341 0.87 SYNJ2 (0.64) IDO1NSD2TDO2KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
EP-4627099-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES Firmenich SA (CH) 2025-10-08 EP disclosed
WO-2024115469-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES FIRMENICH SA (CH) 2024-06-06 WO disclosed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed