Fustin

Fustin

SCHEMBL13640269

O=C1c2ccc(O)cc2O[C@H](c2ccc(O)c(O)c2)[C@H]1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.77
NSD2 O96028 1/20 0.77
TDO2 P48775 1/20 0.77
KDM4E B2RXH2 3/20 0.67
CYP3A4 P08684 3/20 0.67
HSD17B10 Q99714 3/20 0.67
RECQL P46063 2/20 0.67
MAPT P10636 2/20 0.67
ALOX15 P16050 2/20 0.67
MAPK1 P28482 2/20 0.67
SOST Q9BQB4 2/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
GAA P10253 2/20 0.67
NFKB1 P19838 2/20 0.67
POLB P06746 1/20 0.67
CYP1A2 P05177 1/20 0.67
ALOX12 P18054 1/20 0.67
HIF1A Q16665 1/20 0.67
ESR1 P03372 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fustin SCHEMBL555237 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Fustin SCHEMBL29929489 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Fustin SCHEMBL13583362 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Fustin SCHEMBL30443589 1.00 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
SCHEMBL12378836 0.89 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
SCHEMBL12417567 0.89 IDO1 (0.77) IDO1NSD2TDO2KDM4ECYP3A4
Garbanzol SCHEMBL29370332 0.88 ESR1 (0.73) IDO1NSD2TDO2KDM4ECYP3A4
Garbanzol SCHEMBL9663852 0.88 ESR1 (0.73) IDO1NSD2TDO2KDM4ECYP3A4
Garbanzol SCHEMBL29929200 0.88 ESR1 (0.73) IDO1NSD2TDO2KDM4ECYP3A4
Dihydrobinetin SCHEMBL18177341 0.87 SYNJ2 (0.64) IDO1NSD2TDO2KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040081-A1 VACCINIA VIRAL POLYMERASE-MEDIATED VIRAL REPLICATION IMMUNOLUX INTERNATIONAL CORP. 2023-02-09 US disclosed
CN-114965817-A Method for rapidly identifying chemical components of unknown flavonoids in camptotheca acuminata 四川农业大学 2022-08-30 CN disclosed
EP-4017585-A1 FLAVONOID DERIVATIVE FOR TREATING DENTAL CARIES Mühlbauer Technology GmbH (DE) 2022-06-29 EP disclosed
WO-2021032844-A1 FLAVONOID DERIVATIVE FOR TREATING DENTAL CARIES MÜHLBAUER TECHNOLOGY GMBH (DE) 2021-02-25 WO disclosed
US-8859014-B2 Method of converting fustin to fisetin AZI COMPANY LTD. (KR) 2014-10-14 US disclosed
US-8859014-B2 Method of converting fustin to fisetin AZI COMPANY LTD. (KR) 2014-10-14 US disclosed
US-20140031567-A1 Method of Converting Fustin to Fisetin AZI COMPANY LTD. (KR) 2014-01-30 US disclosed
US-20140031567-A1 Method of Converting Fustin to Fisetin AZI COMPANY LTD. (KR) 2014-01-30 US disclosed
US-8551537-B2 Rhus verniciflua stokes extract having increased content of active flavonoid compound and method for preparing same AZI COMPANY LTD. (KR) 2013-10-08 US disclosed
US-8551537-B2 Rhus verniciflua stokes extract having increased content of active flavonoid compound and method for preparing same AZI COMPANY LTD. (KR) 2013-10-08 US disclosed
US-20120283322-A1 Rhus Verniciflua Stokes Extract Having Increased Content Of Active Flavonoid Compound And Method For Preparing Same AZI COMPANY LTD. (KR) 2012-11-08 US disclosed
US-20120283322-A1 Rhus Verniciflua Stokes Extract Having Increased Content Of Active Flavonoid Compound And Method For Preparing Same AZI COMPANY LTD. (KR) 2012-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283322-A1 Rhus Verniciflua Stokes Extract Having Increased Content Of Active Flavonoid Compound And Method For Preparing Same FUS, FLOT1, FIS1 IDO1 4816/4885NSD2 1688/4885TDO2 4645/4885
US-20230040081-A1 VACCINIA VIRAL POLYMERASE-MEDIATED VIRAL REPLICATION POLR1G, POLR1A, POLR1E IDO1 3079/4885NSD2 3205/4885TDO2 2459/4885
US-20140031567-A1 Method of Converting Fustin to Fisetin FUS, RFTN1, HRAS IDO1 4869/4885NSD2 1612/4885TDO2 4744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.