Austrobailignan 6

Austrobailignan 6

SCHEMBL29929564

COc1cc(CC(C)C(C)Cc2ccc3c(c2)OCO3)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 1.00
MAPT P10636 1/20 1.00
ATM Q13315 1/20 1.00
FOS P01100 1/20 0.71
TTR P02766 1/20 0.71
JUN P05412 1/20 0.71
NR3C1 P04150 1/20 0.71
HSD17B1 P14061 1/20 0.71
HSD17B2 P37059 1/20 0.71
ALOX15 P16050 3/20 0.66
ALOX12 P18054 3/20 0.66
CYP3A4 P08684 2/20 0.59
KCNH2 Q12809 1/20 0.58
TAAR1 Q96RJ0 3/20 0.54
SLC6A2 P23975 2/20 0.54
SLC6A4 P31645 2/20 0.54
SLC6A3 Q01959 2/20 0.54
MMP1 P03956 1/20 0.52
CYP2D6 P10635 1/20 0.51
PPARG P37231 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Austrobailignan 6 SCHEMBL1783132 1.00 GAA (1.00) GAAMAPTATMFOSTTR
Austrobailignan 6 SCHEMBL13772405 1.00 GAA (1.00) GAAMAPTATMFOSTTR
Austrobailignan 6 SCHEMBL31238164 1.00 GAA (1.00) GAAMAPTATMFOSTTR
SCHEMBL6733483 0.88 GAA (0.78) GAAMAPTATMFOSTTR
SCHEMBL28659593 0.87 CYP3A4 (0.78) GAAMAPTATMFOSTTR
SCHEMBL13772548 0.87 GAA (0.76) GAAMAPTATMFOSTTR
SCHEMBL30555708 0.86 GAA (0.76) GAAMAPTATMFOSTTR
Mesodihydroguaiaretic Acid SCHEMBL974725 0.84 FOS (1.00) GAAMAPTATMFOSTTR
Dihydroguaiaretic Acid SCHEMBL9087980 0.84 FOS (1.00) GAAMAPTATMFOSTTR
Machilin A SCHEMBL31237868 0.83 TAAR1 (0.74) GAAMAPTATMCYP3A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250009655-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC 2025-01-09 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-12390418-B2 Biphasic compositions comprising one or both of carbonate and phosphate Natural Extraction Systems, LLC (US) 2025-08-19 US disclosed
US-20250009655-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC 2025-01-09 US disclosed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed