Geroquinol

Geroquinol

SCHEMBL29929565

CC(C)=CCC/C(C)=C/Cc1cc(O)ccc1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
ALOX15 P16050 1/20 0.57
PPARG P37231 2/20 0.57
PPARA Q07869 2/20 0.57
CTSK P43235 1/20 0.54
BACE1 P56817 4/20 0.54
PTPN1 P18031 1/20 0.54
MAOB P27338 3/20 0.54
APP P05067 2/20 0.54
OSBP P22059 1/20 0.51
ACHE P22303 3/20 0.51
BCHE P06276 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Geroquinol SCHEMBL557012 1.00 ALOX5 (0.57) ALOX5ALOX15PPARGPPARACTSK
Geroquinol SCHEMBL557013 1.00 ALOX5 (0.57) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL2943955 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL31536036 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
Geranylgeranylhydroquinone SCHEMBL8025990 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL8017471 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL31405831 0.88 ALOX5 (0.58) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL7075584 0.88 ALOX5 (0.58) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL23896921 0.88 MAOB (0.57) PPARGPPARACTSKBACE1PTPN1
SCHEMBL8650303 0.87 ALOX5 (0.57) ALOX5ALOX15PPARGPPARACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
CN-119950464-A Application of small-molecule terpenoid in preparing medicament for treating tumor 广东医科大学附属医院 2025-05-09 CN disclosed
CN-119564649-A Application of geranyl hydroquinone and derivatives thereof in preparation of products for relieving and/or treating rheumatoid arthritis 南方医科大学 2025-03-07 CN disclosed
CN-118853527-A Fungus fermentation liquor and application thereof 徐州医科大学 2024-10-29 CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed