Geroquinol

Geroquinol

SCHEMBL557013

CC(C)=CCCC(C)=CCc1cc(O)ccc1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
ALOX15 P16050 1/20 0.57
PPARG P37231 2/20 0.57
PPARA Q07869 2/20 0.57
CTSK P43235 1/20 0.54
BACE1 P56817 4/20 0.54
PTPN1 P18031 1/20 0.54
MAOB P27338 3/20 0.54
APP P05067 2/20 0.54
OSBP P22059 1/20 0.51
ACHE P22303 3/20 0.51
BCHE P06276 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Geroquinol SCHEMBL557012 1.00 ALOX5 (0.57) ALOX5ALOX15PPARGPPARACTSK
Geroquinol SCHEMBL29929565 1.00 ALOX5 (0.57) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL2943955 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL31536036 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
Geranylgeranylhydroquinone SCHEMBL8025990 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL8017471 0.98 ALOX5 (0.59) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL31405831 0.88 ALOX5 (0.58) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL7075584 0.88 ALOX5 (0.58) ALOX5ALOX15PPARGPPARACTSK
SCHEMBL23896921 0.88 MAOB (0.57) PPARGPPARACTSKBACE1PTPN1
SCHEMBL8650303 0.87 ALOX5 (0.57) ALOX5ALOX15PPARGPPARACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118853527-A Fungus fermentation liquor and application thereof 徐州医科大学 2024-10-29 CN claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 US disclosed
CN-119950464-A Application of small-molecule terpenoid in preparing medicament for treating tumor 广东医科大学附属医院 2025-05-09 CN disclosed
CN-119564649-A Application of geranyl hydroquinone and derivatives thereof in preparation of products for relieving and/or treating rheumatoid arthritis 南方医科大学 2025-03-07 CN disclosed
CN-119564649-A Application of geranyl hydroquinone and derivatives thereof in preparation of products for relieving and/or treating rheumatoid arthritis 南方医科大学 2025-03-07 CN disclosed
US-20060172983-A1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2006-08-03 US disclosed
US-5830996-A ANTITUMOR, ANTICARCINOGENIC AGENT UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-11-03 US disclosed
EP-0855911-A4 NAMENAMICIN, AN ENEDIYNE ANTITUMOR ANTIBIOTIC FROM THE MARINE ASCIDIAN POLYSYNCRATON LITHOSTROTUM UNIV UTAH RES FOUND (US) 1998-10-14 EP disclosed
EP-0855911-A1 NAMENAMICIN, AN ENEDIYNE ANTITUMOR ANTIBIOTIC FROM THE MARINE ASCIDIAN POLYSYNCRATON LITHOSTROTUM UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-08-05 EP disclosed
WO-1998013063-A1 CYCLIC PEPTIDE ANTITUMOR AGENT FROM AN ASCIDIAN UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-04-02 WO disclosed
WO-1997014421-A9 NAMENAMICIN, AN ENEDIYNE ANTITUMOR ANTIBIOTIC FROM THE MARINE ASCIDIAN POLYSYNCRATON LITHOSTROTUM 1997-09-18 WO disclosed
WO-1997014421-A1 NAMENAMICIN, AN ENEDIYNE ANTITUMOR ANTIBIOTIC FROM THE MARINE ASCIDIAN POLYSYNCRATON LITHOSTROTUM UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1997-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB ALOX5 264/4885ALOX15 359/4885PPARG 319/4885
US-20060172983-A1 Functionalized drugs and polymers derived therefrom OGFR, LOX, OPRM1 ALOX5 205/4885ALOX15 52/4885PPARG 2602/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT ALOX5 260/4885ALOX15 657/4885PPARG 3026/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 ALOX5 307/4885ALOX15 233/4885PPARG 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.