Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713981 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTL3MBTL1UTS2RPDGFRB | |
| SCHEMBL29851063 | 0.81 | KDM4E (0.43) | ALDH1A1L3MBTL1UTS2RKMT2AMEN1 | |
| SCHEMBL1671463 | 0.81 | KDM4E (0.43) | ALDH1A1L3MBTL1UTS2RKMT2AMEN1 | |
| SCHEMBL29738543 | 0.79 | TLR8 (0.32) | KMT2AMEN1SMN1; SMN2HSD17B10TLR8 | |
| SCHEMBL16584984 | 0.79 | TLR8 (0.32) | KMT2AMEN1SMN1; SMN2HSD17B10TLR8 | |
| SCHEMBL15530144 | 0.78 | KDM4E (0.44) | ALDH1A1UTS2RKMT2AMEN1NPC1 | |
| SCHEMBL2377913 | 0.77 | LMNA (0.31) | L3MBTL1TLR8POLB | |
| SCHEMBL29693665 | 0.77 | CCR1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2NOS1 | |
| SCHEMBL2379614 | 0.77 | CCR1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2NOS1 | |
| SCHEMBL30275458 | 0.77 | KDM4E (0.39) | ALDH1A1TLR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630670-A | Modulators of TNFalpha activity and uses thereof | 瑞雷拉公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2025038927-A1 | MODULATORS OF TNF ALPHA ACTIVITY AND USES THEREOF | RAYTHERA, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-109311887-B | Pyrazolo [1,5-a ] pyrimidinecarboxamide compounds and their use in the treatment of medical conditions | BIAL研发投资股份有限公司 | 2022-09-13 | — | — | CN | disclosed |