Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630388 | 0.95 | GLO1 (0.39) | TSHRCTSSCTSKGLO1CTSC | |
| SCHEMBL30052724 | 0.90 | TSHR (0.42) | TSHRCTSSCTSKGLO1PTGS1 | |
| SCHEMBL30052069 | 0.87 | TSHR (0.44) | TSHRCTSSCTSKGLO1PTGS1 | |
| SCHEMBL30052277 | 0.87 | MME (0.44) | TSHRCTSSCTSKGLO1PTGS1 | |
| SCHEMBL29591276 | 0.85 | OPRM1 (0.36) | GLO1FNTAFNTB | |
| SCHEMBL30052506 | 0.85 | TSHR (0.47) | TSHRCTSSCTSKGLO1PTGS1 | |
| SCHEMBL2550236 | 0.84 | FNTA (0.47) | LMNAFNTAFNTBPGGT1B | |
| SCHEMBL13093527 | 0.84 | FNTA (0.47) | LMNAFNTAFNTBPGGT1B | |
| SCHEMBL31174313 | 0.84 | FNTA (0.47) | LMNAFNTAFNTBPGGT1B | |
| SCHEMBL2550239 | 0.84 | FNTA (0.47) | LMNAFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367279-A1 | RECOMBINANT HERPES SIMPLEX VIRUS-2 EXPRESSING GLYCOPROTEIN D AND B ANTIGENS | BRIGHAM & WOMENS HOSPITAL INC (US) | 2025-12-04 | — | — | US | disclosed |
| WO-2023240217-A2 | RECOMBINANT HERPES SIMPLEX VIRUS-2 EXPRESSING GLYCOPROTEIN D AND B ANTIGENS | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| US-11390650-B2 | Recombinant Herpes Simplex Virus-2 expressing glycoprotein B and D antigens | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2022-07-19 | — | — | US | disclosed |