Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | PARL | Q9H300 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77999 | 1.00 | MEN1 (0.56) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL5166507 | 0.95 | MAPT (0.57) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL85664 | 0.93 | MAPT (0.60) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL11183530 | 0.89 | MAPT (0.53) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL11142367 | 0.83 | ALDH1A1 (0.74) | RAB9AALDH1A1AKR1C3HPGDL3MBTL1 | |
| SCHEMBL5632220 | 0.81 | MAPT (0.53) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL17206015 | 0.81 | MAPT (0.43) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL3223479 | 0.81 | KMT2A (0.61) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL30962697 | 0.81 | SIRT6 (0.62) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL14881010 | 0.80 | MAPT (0.51) | MEN1KMT2ARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043768-A | Method for synthesizing N-aryl pyrrolidine-2-ketone by acid-promoted ring opening of cyclopropyl | 新乡市润宇新材料科技有限公司 | 2022-09-13 | — | — | CN | disclosed |