SCHEMBL2993005

SCHEMBL2993005

CCc1ccc(C(=O)[C@@H]2CC[C@H](C(=O)O)C2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
S1PR1 P21453 1/20 0.47
S1PR5 Q9H228 1/20 0.47
MGLL Q99685 1/20 0.46
PLK1 P53350 1/20 0.42
GRIK2 Q13002 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C1 Q04828 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2993000 1.00 ALDH1A1 (0.50) ALDH1A1S1PR1S1PR5MGLLPLK1
SCHEMBL2993003 1.00 ALDH1A1 (0.50) ALDH1A1S1PR1S1PR5MGLLPLK1
SCHEMBL3678830 0.86 MGLL (0.56) ALDH1A1MGLLPLK1NPC1RAB9A
SCHEMBL2980743 0.79 AKR1C3 (0.56) MGLLNPC1RAB9AAKR1C3AKR1C1
SCHEMBL2980746 0.79 AKR1C3 (0.56) MGLLNPC1RAB9AAKR1C3AKR1C1
SCHEMBL2980744 0.79 AKR1C3 (0.56) MGLLNPC1RAB9AAKR1C3AKR1C1
SCHEMBL10229518 0.78 SRD5A2 (0.57) ALDH1A1MGLLPLK1NPC1RAB9A
SCHEMBL2992510 0.77 NPC1 (0.69) ALDH1A1MGLLNPC1RAB9AMEN1
SCHEMBL2992502 0.77 NPC1 (0.69) ALDH1A1MGLLNPC1RAB9AMEN1
SCHEMBL2992505 0.77 NPC1 (0.69) ALDH1A1MGLLNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8444774-B2 Flux composition and process for use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-05-21 US disclosed
US-7780801-B2 for soldering flip chip surfaces; fluxing agent comprises keto acid such as levulinic acid or acetylbutyric acid; mixture of tacky solvent (ethoxylated glycerol) with non-tacky solvent (methanol) INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-08-24 US disclosed
US-20100175790-A1 New Flux Composition and Process For Use Thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-07-15 US disclosed
US-20080124568-A1 New flux composition and process for use thereof GLOBALFOUNDRIES INC. (KY) 2008-05-29 US disclosed