SCHEMBL29930119

SCHEMBL29930119

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.87

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 16/20 0.87
▸ NTSR2 O95665 12/20 0.87
▸ SORT1 Q99523 9/20 0.80
▸ NPY1R P25929 1/20 0.74
▸ OPRM1 P35372 1/20 0.71
▸ OPRD1 P41143 1/20 0.71
▸ OPRK1 P41145 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30472155 0.94 NTSR1 (0.87) NTSR1NTSR2SORT1
SCHEMBL29398203 0.94 NTSR1 (0.87) NTSR1NTSR2SORT1
SCHEMBL29416842 0.94 NTSR1 (0.87) NTSR1NTSR2SORT1
Demotensin 1 SCHEMBL30312742 0.88 NTSR1 (1.00) NTSR1NTSR2SORT1OPRD1
SCHEMBL29442471 0.88 NTSR1 (0.71) NTSR1NTSR2SORT1NPY1ROPRM1
SCHEMBL29361023 0.86 NTSR1 (0.74) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL31280899 0.86 NTSR1 (0.74) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL1421733 0.85 NTSR1 (0.74) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL1421754 0.85 NTSR1 (0.74) NTSR1NTSR2SORT1OPRM1OPRD1
SCHEMBL30880437 0.85 NTSR1 (0.82) NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154219-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2025-05-15 — — US disclosed
US-12110318-B2 Peptide analogs ADEPTHERA LLC (US) 2024-10-08 — — US disclosed
US-20220324935-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2022-10-13 — — US disclosed
US-11390657-B2 Peptide analogs ADEPTHERA LLC (US) 2022-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12110318-B2 Peptide analogs RAMP1, RAMP3, RAMP2 NTSR1 18/4885NTSR2 25/4885SORT1 1025/4885
US-20220324935-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 NTSR1 23/4885NTSR2 44/4885SORT1 1460/4885
US-20250154219-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 NTSR1 23/4885NTSR2 44/4885SORT1 1460/4885
US-11390657-B2 Peptide analogs RAMP1, RAMP3, RAMP2 NTSR1 18/4885NTSR2 25/4885SORT1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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