SCHEMBL29398203

SCHEMBL29398203

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.87

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 16/20 0.87
▸ NTSR2 O95665 15/20 0.87
▸ SORT1 Q99523 12/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30472155 1.00 NTSR1 (0.87) NTSR1NTSR2SORT1
SCHEMBL29416842 1.00 NTSR1 (0.87) NTSR1NTSR2SORT1
SCHEMBL29930119 0.94 NTSR1 (0.87) NTSR1NTSR2SORT1
SCHEMBL30880437 0.91 NTSR1 (0.82) NTSR1NTSR2SORT1
SCHEMBL31280899 0.90 NTSR1 (0.74) NTSR1NTSR2SORT1
SCHEMBL29361023 0.90 NTSR1 (0.74) NTSR1NTSR2SORT1
SCHEMBL30034783 0.89 NTSR2 (0.73) NTSR1NTSR2SORT1
SCHEMBL30037824 0.89 NTSR2 (0.73) NTSR1NTSR2SORT1
SCHEMBL29533517 0.88 NTSR1 (0.82) NTSR1NTSR2SORT1
Proctolin SCHEMBL30163458 0.87 NTSR1 (0.71) NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329827-A1 TARGETING SYSTEM FOR CANCER COMPRISING A RADIOISOTOPE Alphathera AG (CH) 2024-03-06 — — EP claimed
WO-2022231424-A1 TARGETING SYSTEM FOR CANCER COMPRISING A RADIOISOTOPE ALPHATHERA AG (CH) 2022-11-03 — — WO claimed
EP-3432934-B1 PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS Bayer Pharma AG (DE) 2022-02-23 — — EP claimed
EP-4731658-A1 TRANSFERRIN RECEPTOR-BINDING MOLECULES, CONJUGATES THEREOF AND THEIR USES TO PREVENT OR TREAT NERVOUS SYSTEM DISEASES Vect-Horus (FR) 2026-04-29 — — EP disclosed
US-20260078095-A1 NEUROTENSIN RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2026-03-19 — — US disclosed
US-20250382633-A1 ADENOVIRAL VECTORS UNIV ZUERICH (CH) 2025-12-18 — — US disclosed
US-12485191-B2 Radiopharmaceuticals and methods of use thereof BOARD OF REGENTS OF THE UNIVERISTY OF NEBRASKA (US) 2025-12-02 — — US disclosed
US-20250332298-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES BLUE WAVE THERAPEUTICS GMBH (CH) 2025-10-30 — — US disclosed
US-12453757-B2 Method for ameliorating autism symptoms by pharmacological activation of the neurotensin receptor 1 (NTSR1) NEW YORK INSTITUTE OF TECHNOLOGY (US) 2025-10-28 — — US disclosed
US-20250304677-A1 Blood-Cerebrospinal Fluid Barrier Crossing Antibodies KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-10-02 — — US disclosed
US-12358948-B2 Neurotensinergic agonists and methods of using same preventing or treating pain SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2025-07-15 — — US disclosed
EP-3712131-B1 NEUROTENSIN RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-02-01 — — EP disclosed
WO-2022231424-A1 TARGETING SYSTEM FOR CANCER COMPRISING A RADIOISOTOPE ALPHATHERA AG (CH) 2022-11-03 — — WO disclosed
US-20220315632-A1 COMBINATION OF DIETARY PEPTIDES DIET4LIFE APS (DK) 2022-10-06 — — US disclosed
US-20220248736-A1 DIETARY PEPTIDES DIET4LIFE APS (DK) 2022-08-11 — — US disclosed
CN-109320502-B Neurotensin receptor ligands 3B制药有限公司 2022-06-07 — — CN disclosed
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2022-06-02 — — US disclosed
US-11259554-B2 Dietary peptides DIET4LIFE APS (DK) 2022-03-01 — — US disclosed
US-20220056077-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE RATNER, Cecilia (DK) 2022-02-24 — — US disclosed
EP-3432934-B1 PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS Bayer Pharma AG (DE) 2022-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485191-B2 Radiopharmaceuticals and methods of use thereof FOLH1, SSTR4, SLC18A2 NTSR1 139/4885NTSR2 77/4885SORT1 1051/4885
US-12453757-B2 Method for ameliorating autism symptoms by pharmacological activation of the neurotensin receptor 1 (NTSR1) NTSR1, NTSR2, NPSR1 NTSR1 1/4885NTSR2 2/4885SORT1 393/4885
US-20250382633-A1 ADENOVIRAL VECTORS DARS1, DBN1, DBNL NTSR1 2854/4885NTSR2 3498/4885SORT1 532/4885
US-20250332298-A1 PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES ALG1, ALG3, GRPR NTSR1 1009/4885NTSR2 1530/4885SORT1 2495/4885
US-11259554-B2 Dietary peptides GLP1R, HDGF, VIP NTSR1 28/4885NTSR2 40/4885SORT1 593/4885
US-12358948-B2 Neurotensinergic agonists and methods of using same preventing or treating pain VIP, NTSR2, VIPR2 NTSR1 5/4885NTSR2 2/4885SORT1 3892/4885
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN VIP, NTSR2, VIPR2 NTSR1 5/4885NTSR2 2/4885SORT1 3892/4885
US-20260078095-A1 NEUROTENSIN RECEPTOR LIGANDS NTSR1, NTSR2, GRPR NTSR1 1/4885NTSR2 2/4885SORT1 2100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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