Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5912601 | 0.74 | HRH3 (0.67) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| SCHEMBL21641504 | 0.71 | KDM4E (0.44) | HRH3CYP3A4CYP2C19KCNH2ALDH1A1 | |
| SCHEMBL5912645 | 0.70 | HRH3 (0.62) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| SCHEMBL3977413 | 0.70 | HRH3 (1.00) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| SCHEMBL3968098 | 0.70 | HRH3 (0.65) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| Hydrochloric Acid SCHEMBL3972495 | 0.69 | HRH3 (0.97) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| Hydrochloric Acid SCHEMBL3975852 | 0.69 | HRH3 (0.64) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| SCHEMBL21641390 | 0.69 | DRD2 (0.51) | DRD2DRD3ALDH1A1 | |
| SCHEMBL5912927 | 0.69 | HRH3 (0.59) | HRH3HTR1ACYP3A4CYP2C19CYP2C8 | |
| SCHEMBL14894663 | 0.69 | HRH3 (0.50) | HRH3HTR1ACYP3A4CYP2C19SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989173-B | Imidazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114989173-A | Imidazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2022-09-02 | — | — | CN | disclosed |