Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 6/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21641504 | 0.80 | KDM4E (0.44) | NOTUMMAOBKDM4EALDH1A1TSHR | |
| SCHEMBL15800697 | 0.73 | DRD2 (0.79) | DRD2DRD3NOTUMALOX5NSD2 | |
| SCHEMBL105023 | 0.73 | SIGMAR1 (0.41) | KDM4EMAPTHTT | |
| SCHEMBL6272216 | 0.73 | SIGMAR1 (0.41) | KDM4EMAPTHTT | |
| SCHEMBL21641415 | 0.72 | CYP11B2 (0.40) | KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL16789934 | 0.70 | DRD2 (0.59) | DRD2DRD3NOTUMALOX5NSD2 | |
| SCHEMBL29809089 | 0.70 | DRD2 (0.74) | DRD2DRD3NOTUMALOX5NSD2 | |
| SCHEMBL3537217 | 0.70 | DRD2 (0.74) | DRD2DRD3NOTUMALOX5NSD2 | |
| SCHEMBL4468086 | 0.69 | DRD2 (0.72) | DRD2DRD3NOTUMALOX5NSD2 | |
| SCHEMBL29930534 | 0.69 | HRH3 (0.54) | DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234630-B | Phenylimidazolines having aminomethyl groups Compound or salt thereof and process for producing the same | 三菱瓦斯化学株式会社 | 2023-02-03 | — | — | CN | claimed |
| EP-3604286-B1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD OF SAID COMPOUNDS OR SALTS THEREOF | MITSUBISHI GAS CHEMICAL CO (JP) | 2022-01-19 | — | — | EP | claimed |
| CN-110234630-B | Phenylimidazolines having aminomethyl groups Compound or salt thereof and process for producing the same | 三菱瓦斯化学株式会社 | 2023-02-03 | — | — | CN | disclosed |
| EP-3604286-B1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD OF SAID COMPOUNDS OR SALTS THEREOF | MITSUBISHI GAS CHEMICAL CO (JP) | 2022-01-19 | — | — | EP | disclosed |
| US-11198676-B2 | Phenyl imidazoline compound having aminomethyl group or salt thereof, or phenyl tetrahydropyrimidine compound having aminomethyl group or salt thereof, and production method for such compounds or salts thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-12-14 | — | — | US | disclosed |
| US-20200339516-A1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD FOR SUCH COMPOUNDS OR SALTS THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-10-29 | — | — | US | disclosed |
| EP-3604286-A1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD OF SAID COMPOUNDS OR SALTS THEREOF | Mitsubishi Gas Chemical Company, Inc. (JP) | 2020-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339516-A1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD FOR SUCH COMPOUNDS OR SALTS THEREOF | JAK2, IL4I1, INMT | DRD2 1282/4885DRD3 1755/4885NOTUM 938/4885 |
| US-11198676-B2 | Phenyl imidazoline compound having aminomethyl group or salt thereof, or phenyl tetrahydropyrimidine compound having aminomethyl group or salt thereof, and production method for such compounds or salts thereof | JAK2, IL4I1, INMT | DRD2 1282/4885DRD3 1755/4885NOTUM 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.