SCHEMBL29930713

SCHEMBL29930713

O=P(O)(O)O[C@@H]1C(O)[C@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)C(OP(=O)(O)OP(=O)(O)O)[C@H]1OP(=O)(O)O

nearest known ligand 0.88

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 8/20 0.71
ITPR2 Q14571 4/20 0.71
ITPR1 Q14643 4/20 0.71
INPPL1 O15357 1/20 0.71
AKT1 P31749 1/20 0.71
INPP5A Q14642 2/20 0.64
SMPD1 P17405 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7035469 1.00 ITPR3 (0.71) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL4343592 0.96 ITPR3 (0.74) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL4343591 0.96 ITPR3 (0.74) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL7715053 0.93 ITPR3 (0.67) ITPR3ITPR2ITPR1INPPL1AKT1
Scyllitol SCHEMBL5997336 0.91 ITPR3 (0.64) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL6664274 0.91 ITPR3 (0.74) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL19712150 0.91 ITPR3 (0.58) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL3498450 0.91 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL613185 0.91 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL3500008 0.91 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461828-B IP6K inhibitors 武田药品工业株式会社 2022-07-19 CN disclosed