SCHEMBL2993091

SCHEMBL2993091

CCCC(C)=NNC(=O)c1ccncc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
TDP1 Q9NUW8 1/20 0.58
GAA P10253 8/20 0.57
MAPT P10636 5/20 0.57
ALDH1A1 P00352 4/20 0.57
IDE P14735 1/20 0.57
KMT2A Q03164 4/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 3/20 0.54
LMNA P02545 1/20 0.54
GFER P55789 1/20 0.52
CYP3A4 P08684 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2993090 1.00 KDM4E (0.58) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL2998244 0.91 OGG1 (0.61) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL2998242 0.91 OGG1 (0.61) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL6635773 0.87 KDM4E (0.60) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL2991665 0.87 KDM4E (0.60) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL2991662 0.87 KDM4E (0.60) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL2999232 0.86 GAA (0.60) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL3003222 0.84 GAA (0.63) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL3003219 0.84 GAA (0.63) KDM4ETDP1GAAMAPTALDH1A1
SCHEMBL3003239 0.84 KDM4E (0.54) KDM4ETDP1GAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP claimed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
US-9617404-B2 Rubber composition, conveyor belt rubber composition, conveyor belt, and belt conveyor device BRIDGESTONE CORPORATION (JP) 2017-04-11 US disclosed
US-20160122519-A1 RUBBER COMPOSITION, CONVEYOR BELT RUBBER COMPOSITION, CONVEYOR BELT, AND BELT CONVEYOR DEVICE BRIDGESTONE CORPORATION (JP) 2016-05-05 US disclosed
US-20100184811-A1 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) 2010-07-22 US disclosed
EP-2068873-A2 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS Pharma 2100 (DK) 2009-06-17 EP disclosed
WO-2008031440-A2 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS PHARMA 2100 (DK) 2008-03-20 WO disclosed
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 US disclosed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184811-A1 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS ODC1, OTC, ACACB KDM4E 3169/4885TDP1 3641/4885GAA 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.