Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611714 | 1.00 | SGMS2 (0.58) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL6748166 | 0.89 | SGMS2 (0.72) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL23231164 | 0.87 | SGMS2 (0.61) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL7050350 | 0.86 | PTGER1 (0.61) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL28731423 | 0.85 | HDAC6 (0.57) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL5940976 | 0.84 | SGMS2 (0.54) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL29930977 | 0.84 | SGMS2 (0.54) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL23611722 | 0.83 | NPC1 (0.68) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL29930700 | 0.83 | NPC1 (0.68) | SGMS2GAANPC1ALDH1A1MAPT | |
| SCHEMBL22568217 | 0.83 | NPC1 (0.56) | SGMS2GAANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210229-A | Polycyclic amides as UBE2K modulators for the treatment of cancer | 博格有限责任公司 | 2022-10-18 | — | — | CN | disclosed |