Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142769 | 0.89 | KMT2A (0.72) | SGMS2NPC1KMT2AMEN1LMNA | |
| SCHEMBL23611714 | 0.89 | SGMS2 (0.58) | SGMS2NPC1GAAKMT2AMEN1 | |
| SCHEMBL29930939 | 0.89 | SGMS2 (0.58) | SGMS2NPC1GAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2451523 | 0.88 | KMT2A (0.71) | SGMS2NPC1KMT2AMEN1LMNA | |
| SCHEMBL1346595 | 0.88 | SGMS2 (0.58) | SGMS2NPC1GAAKMT2AMEN1 | |
| SCHEMBL974381 | 0.87 | SGMS2 (0.72) | SGMS2NPC1GAAKMT2AMEN1 | |
| SCHEMBL22568217 | 0.87 | NPC1 (0.56) | SGMS2NPC1GAAKMT2AMEN1 | |
| SCHEMBL28731423 | 0.86 | HDAC6 (0.57) | SGMS2NPC1GAAKMT2AMEN1 | |
| SCHEMBL14428116 | 0.85 | SGMS2 (0.75) | SGMS2NPC1GAAKMT2AMEN1 | |
| SCHEMBL22568219 | 0.84 | MCL1 (0.57) | SGMS2NPC1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008017-A | Covalent organic frameworks and methods of making and using same | 新加坡国立大学 | 2022-02-01 | — | — | CN | claimed |
| US-20220306812-A1 | COVALENT ORGANIC FRAMEWORK AND METHODS OF FABRICATION AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-09-29 | — | — | US | disclosed |
| CN-114008017-A | Covalent organic frameworks and methods of making and using same | 新加坡国立大学 | 2022-02-01 | — | — | CN | disclosed |
| US-20130072461-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2013-03-21 | — | — | US | disclosed |
| US-8329736-B2 | Triazole compounds that modulate HSP90 activity | SYNTA PHARMACEUTICALS, CORP. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120202813-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2012-08-09 | — | — | US | disclosed |
| US-8183384-B2 | Triazole compounds that modulate HSP90 activity | SYNTA PHARMACEUTICALS CORP. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20080004277-A1 | Triazole compounds that modulate HSP90 activity | LSI FINANCING LLC, AS ADMINISTRATIVE AGENT | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004277-A1 | Triazole compounds that modulate HSP90 activity | HSP90AB1, HSP90B1, HSP90AA1 | SGMS2 4585/4885NPC1 1235/4885GAA 1052/4885 |
| US-20120202813-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | HSP90AB1, HSP90B1, HSP90AA1 | SGMS2 4585/4885NPC1 1235/4885GAA 1052/4885 |
| US-20130072461-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | HSP90AB1, HSP90B1, HSP90AA1 | SGMS2 4585/4885NPC1 1235/4885GAA 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.