Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 7/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932129 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL23536478 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL29932117 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL29772926 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL23536460 | 0.70 | GAA (0.46) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL29931915 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL29931975 | 0.69 | DRD4 (0.35) | SMN1; SMN2ALDH1A1LMNATP53GAA | |
| SCHEMBL29932039 | 0.68 | POLB (0.38) | SMN1; SMN2ALDH1A1DRD2ADRA1DADRA1A | |
| SCHEMBL29931848 | 0.67 | GRM2 (0.39) | SMN1; SMN2ALDH1A1GAADRD2ADRA1D | |
| SCHEMBL23536443 | 0.67 | F10 (0.46) | GAAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |