Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493517 | 0.96 | TDP1 (0.41) | TDP1ALDH1A1HSD17B10CTSDTSHR | |
| SCHEMBL31548607 | 0.83 | TDP1 (0.33) | TDP1ALDH1A1HSD17B10CTSDTSHR | |
| SCHEMBL6694506 | 0.67 | TDP1 (0.37) | TDP1ALDH1A1HSD17B10CTSDTSHR | |
| Triphenylene SCHEMBL28735679 | 0.65 | HPRT1 (0.53) | TDP1ALDH1A1HSD17B10TSHRALOX12 | |
| Diphenylamine SCHEMBL28257671 | 0.61 | HSD17B10 (0.92) | TDP1ALDH1A1HSD17B10CTSDTSHR | |
| Biphenyl SCHEMBL29839700 | 0.61 | ALDH1A1 (0.90) | TDP1ALDH1A1HSD17B10MAPK1LMNA | |
| Biphenyl SCHEMBL1157981 | 0.61 | ALDH1A1 (0.90) | TDP1ALDH1A1HSD17B10MAPK1LMNA | |
| Biphenyl SCHEMBL36559 | 0.61 | ALDH1A1 (0.90) | TDP1ALDH1A1HSD17B10MAPK1LMNA | |
| SCHEMBL1006251 | 0.59 | HPRT1 (0.57) | TDP1ALDH1A1HSD17B10TSHRALOX12 | |
| SCHEMBL30977781 | 0.59 | HPRT1 (0.57) | TDP1ALDH1A1HSD17B10TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210418-A | Core-sheath filaments having a curable composition in the core | 3M创新有限公司 | 2022-10-18 | — | — | CN | disclosed |