Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 8/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611067 | 0.81 | PDCD1 (0.46) | PDCD1CD274DPP4 | |
| SCHEMBL30916147 | 0.77 | CREBBP (0.39) | CNR2PDCD1CD274PIK3R1PIK3CA | |
| SCHEMBL29716001 | 0.76 | PDCD1 (0.41) | PDCD1CD274PIK3R1PIK3CADPP4 | |
| SCHEMBL30340518 | 0.76 | PDCD1 (0.43) | PDCD1CD274 | |
| SCHEMBL30703775 | 0.75 | PDCD1 (0.42) | CNR2PDCD1CD274DPP4 | |
| SCHEMBL29022800 | 0.75 | PDCD1 (0.52) | PDCD1CD274F12 | |
| SCHEMBL30966759 | 0.74 | PDCD1 (0.39) | PDCD1CD274 | |
| SCHEMBL29022813 | 0.72 | PDCD1 (0.54) | PDCD1CD274DPP4 | |
| SCHEMBL31125637 | 0.72 | PDCD1 (0.38) | CNR2PDCD1CD274DPP4 | |
| SCHEMBL30340703 | 0.72 | CNR2 (0.41) | CNR2PDCD1CD274PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |