SCHEMBL2993336

SCHEMBL2993336

Cc1cccc2c1C(=O)C(=O)c1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.59
PTPRC P08575 4/20 0.59
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
MAPT P10636 3/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
LMNA P02545 3/20 0.59
MAPK1 P28482 2/20 0.59
KDM4E B2RXH2 2/20 0.59
APAF1 O14727 2/20 0.59
TDP2 O95551 2/20 0.59
PLA2G1B P04054 2/20 0.59
POLB P06746 2/20 0.59
PLCG1 P19174 2/20 0.59
S100A4 P26447 2/20 0.59
PPARG P37231 2/20 0.59
HTT P42858 2/20 0.59
GALK1 P51570 2/20 0.59
BLM P54132 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908547 0.95 SMN1; SMN2 (0.55) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL3976848 0.95 SMN1; SMN2 (0.55) SMN1; SMN2PTPRCNPC1RAB9AMAPT
Water SCHEMBL27388116 0.93 SMN1; SMN2 (0.53) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL4161497 0.88 CA1 (0.52) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL29634210 0.88 CA1 (0.52) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL14852073 0.86 PTPRC (0.63) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL224650 0.86 ALDH1A1 (0.66) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL30580334 0.86 ALDH1A1 (0.66) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL1480100 0.84 MAPT (0.50) SMN1; SMN2PTPRCNPC1RAB9AMAPT
SCHEMBL6036681 0.83 TDP2 (0.52) SMN1; SMN2PTPRCNPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100180937-A1 HOLOGRAPHIC ENERGY-COLLECTING MEDIUM AND ASSOCIATED DEVICE GENERAL ELECTRIC COMPANY (US) 2010-07-22 US disclosed
US-4069123-A ALKYL ACRYLATE OR METHACRYLATE HOMO- OR COPOLYMER WITH QUINONE TYPE ULTRAVIOLET SENSITIZER NATIONAL STARCH & CHEMICAL CORPORATION (US) 1978-01-17 US disclosed