Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.46 |
| ▸ | LPL | P06858 | 10/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28843389 | 1.00 | LIPG (0.46) | LIPGLPLOPRM1OPRK1OPRL1 | |
| SCHEMBL22290862 | 0.91 | LIPG (0.42) | LIPGLPLROCK1IRAK4F11 | |
| SCHEMBL30765291 | 0.88 | LIPG (0.43) | LIPGLPLROCK1IRAK4F11 | |
| SCHEMBL28579043 | 0.82 | LPL (0.33) | LIPGLPLOPRM1OPRK1OPRL1 | |
| SCHEMBL24175626 | 0.81 | LIPG (0.46) | LIPGLPLROCK1IRAK4CA1 | |
| SCHEMBL30404611 | 0.81 | LIPG (0.46) | LIPGLPLROCK1IRAK4CA1 | |
| SCHEMBL16428162 | 0.80 | LPL (0.50) | LIPGLPLOPRM1OPRK1OPRL1 | |
| SCHEMBL22721855 | 0.79 | AKR1C1 (0.42) | LIPGLPLROCK1F11P4HB | |
| SCHEMBL1476213 | 0.78 | LIPG (0.59) | LIPGLPLIRAK4F11P4HB | |
| SCHEMBL22290338 | 0.78 | LIPG (0.43) | LIPGLPLROCK1IRAK4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |