Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.67 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795380 | 0.87 | ALDH1A1 (0.52) | PARP1DHODHKDM4ELMNATP53 | |
| SCHEMBL6442515 | 0.80 | PARP1 (1.00) | PARP1PARP2DHODHKDM4EPARP3 | |
| SCHEMBL31061508 | 0.80 | PARP1 (1.00) | PARP1PARP2DHODHKDM4EPARP3 | |
| SCHEMBL30161751 | 0.80 | PARP1 (0.55) | PARP1PARP2DHODHNPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL30161649 | 0.79 | PARP1 (0.54) | PARP1PARP2DHODHNPSR1RXFP1 | |
| SCHEMBL29933466 | 0.78 | PARP1 (0.78) | PARP1PARP2 | |
| SCHEMBL2943452 | 0.77 | GRM5 (0.54) | PARP1PARP2DHODHNPSR1RXFP1 | |
| SCHEMBL29959688 | 0.77 | PARP1 (1.00) | PARP1KDM4ELMNA | |
| SCHEMBL460456 | 0.77 | PARP1 (1.00) | PARP1KDM4ELMNA | |
| SCHEMBL29923346 | 0.77 | PARP1 (1.00) | PARP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |