Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.53 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893898 | 0.83 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPK1NPSR1NOTUM | |
| SCHEMBL2160181 | 0.77 | ALDH1A1 (0.61) | CD274PDCD1LG2KDM4EALDH1A1S1PR1 | |
| SCHEMBL30377416 | 0.75 | ALDH1A1 (0.62) | KDM4EALDH1A1MAPK1NPSR1NOTUM | |
| SCHEMBL4662897 | 0.75 | KDM4E (0.54) | CD274PDCD1LG2KDM4ETSHRALDH1A1 | |
| SCHEMBL5107192 | 0.75 | KDM4E (0.54) | CD274PDCD1LG2KDM4ETSHRALDH1A1 | |
| SCHEMBL5110651 | 0.74 | TSHR (0.60) | CD274PDCD1LG2KDM4ETSHRALDH1A1 | |
| SCHEMBL21379806 | 0.74 | KDM4E (0.49) | RAB9AKDM4ETSHRALDH1A1NOTUM | |
| SCHEMBL4664465 | 0.74 | TSHR (0.60) | CD274PDCD1LG2KDM4ETSHRALDH1A1 | |
| SCHEMBL4724721 | 0.73 | ALDH1A1 (0.85) | CD274PDCD1LG2ALDH1A1S1PR1NOTUM | |
| SCHEMBL7461309 | 0.73 | PDCD1 (0.63) | CD274KDM4ETSHRALDH1A1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |