Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18530849 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTALOX15CSNK2A1MAOB | |
| SCHEMBL11508309 | 0.88 | MAOB (0.61) | SMN1; SMN2MAPTALOX15MAOBCA12 | |
| SCHEMBL10898831 | 0.86 | MAOB (0.56) | SMN1; SMN2MAPTALOX15CSNK2A1MAOB | |
| SCHEMBL29933496 | 0.86 | MAOB (0.56) | SMN1; SMN2MAPTALOX15CSNK2A1MAOB | |
| SCHEMBL15447330 | 0.81 | MAPT (0.53) | SMN1; SMN2MAPTALOX15MAOBNPC1 | |
| SCHEMBL204082 | 0.80 | PIM1 (0.54) | SMN1; SMN2MAPTMAOBCA12CA1 | |
| SCHEMBL23359886 | 0.79 | KEAP1 (0.46) | SMN1; SMN2CSNK2A1MAOBCA1CA2 | |
| SCHEMBL31704456 | 0.79 | KDM4E (0.50) | MAPTALOX15CSNK2A1MAOBNPC1 | |
| SCHEMBL23320560 | 0.79 | KDM4E (0.50) | MAPTALOX15CSNK2A1MAOBNPC1 | |
| SCHEMBL11513004 | 0.78 | MAOB (0.67) | SMN1; SMN2MAPTMAOBNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |